Role of low-level laser therapy in neurorehabilitation.
نویسندگان
چکیده
This year marks the 50th anniversary of the discovery of the laser. The development of lasers for medical use, which became known as low-level laser therapy (LLLT) or photobiomodulation, followed in 1967. In recent years, LLLT has become an increasingly mainstream modality, especially in the areas of physical medicine and rehabilitation. At first used mainly for wound healing and pain relief, the medical applications of LLLT have broadened to include diseases such as stroke, myocardial infarction, and degenerative or traumatic brain disorders. This review will cover the mechanisms of LLLT that operate both on a cellular and a tissue level. Mitochondria are thought to be the principal photoreceptors, and increased adenosine triphosphate, reactive oxygen species, intracellular calcium, and release of nitric oxide are the initial events. Activation of transcription factors then leads to expression of many protective, anti-apoptotic, anti-oxidant, and pro-proliferation gene products. Animal studies and human clinical trials of LLLT for indications with relevance to neurology, such as stroke, traumatic brain injury, degenerative brain disease, spinal cord injury, and peripheral nerve regeneration, will be covered.
منابع مشابه
Role of low level laser in ameliorating the damaging effects of gamma irradiation on mice liver
Background: Exposure to ionizing radiation is inevitable. Using of low-level laser therapy (LLLT) stimulates tissue repair and reduces inflammation. The objective of the present study aimed at evaluating the therapeutic efficacy of Helium-Neon (He-Ne) laser in stimulating the reparative processes in the liver of mice after whole body gamma-irradiation (WBγ-I). Materials and Methods: Two hundred...
متن کاملLow Level Laser Therapy in Treatment of Diabetic Foot Ulcers: Double Blind Controlled Clinical Trial
متن کامل
Effect of adjunctive low level laser therapy on gingival graft: A Review of the Literature
Introduction: Mucogingival surgery is performed to correct defects in the morphology, position, and/or amount of gingiva. Such post-operative complications as bleeding, swelling, and pain have often been documented after mucogingival surgery and are associated with discomfort after surgery. The low-intensity laser has been used to promote analgesia. Low level laser therapy (LLLT) not only accel...
متن کاملEffect of Low Frequency Low-Level Infra-Red Diode Laser Therapy on Third Degree Burn Healing in Rats Skin
Purpose: The aim of present investigation was to evaluate low frequency low-level infra red diode laser therapy for a third degree burn healing in rats skin.Materials and Methods: 36 rats were divided into groups one and two. On day zero three third degree burns were made on the dorsum of each rat by steam. In group one ,first burn were exposed to a 80 Hz –pulsed 890 nm infra red diode laser wi...
متن کاملEffect of Low Frequency Low-Level Infra-Red Diode Laser Therapy on Third Degree Burn Healing in Rats Skin
Purpose: The aim of present investigation was to evaluate low frequency low-level infra red diode laser therapy for a third degree burn healing in rats skin.Materials and Methods: 36 rats were divided into groups one and two. On day zero three third degree burns were made on the dorsum of each rat by steam. In group one ,first burn were exposed to a 80 Hz –pulsed 890 nm infra red diode laser wi...
متن کاملThe Effects of Low Level Laser Therapy on the Expression of Collagen Type I Gene and Proliferation of Human Gingival Fibroblasts (Hgf3-Pi 53): in vitro Study
Objective(s): Recent investigations show that both proliferation and secretion of macromolecules by cells can be regulated by low level laser therapy (LLLT). The aim of this study was to determine whether LLLT could induce a bio-stimulatory effects on human gingival fibroblasts (HGF3-PI 53). Therefore, the effect of laser irradiation on human gingival cell proliferation and collage...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- PM & R : the journal of injury, function, and rehabilitation
دوره 2 12 Suppl 2 شماره
صفحات -
تاریخ انتشار 2010